Side Effects of Xalatan Eye Drops
1- On Cornea
Burning sensation, Blurred of vision which can be temporary after each eye drop or due to dry eyes, eye pain, foreign body sensation, punctuate keratopathy. Sometimes xalatan application can flare up previous Herpes Eye Infection.
2- On Conjunctiva
Conjunctival hyperemia with eye redness, sometimes patient can’t tolerated the redness and this can lead to discontinuation of medication.
3- On Eyelid
Swelling, crusting, itching and pigmentation. This pigmentation that can occur in the eyelid and the skin around the eye can be reversible when the medication is discontinued.
4- On Eyelashes
This is one of the most common side effects of Xalatan. Some patients consider it as an advantage rather than side effect. In fact there is a prostaglandin analogue eye drops similar to Xalatans that is used to enhance eyelashes growth in patients with hypotrichosis and this medication is called Latisse.
After prolong usage of xalatan eye drops which can range from 5 months to years, the eyelashes will show some changes such as increasing in length, thickness, number of the lashes and also increase of the pigmentation.
Those eyelashes can have misdirected growth in which they will grow toward the cornea causing injuries to the corneal surface. This complication can be reversible in some cases when the medication is discontinued.
Xalatan eye drops can increase iris pigmentation and a different color of the iris with prolongs use will occur. This pigmentation is irreversible in most of the cases even after discontinuation of medication.
These color changes occurs mainly in patients with light iris color and in most of the patients it occurs within the first year of treatment.
6- Iritis and Uveitis
Xalatan eye drops can disrupt the blood ocular barrier which helps to prevent most of the blood components to pass to aqueous humor and vitreous body. This barrier can be disrupted by latanoprost causing cells and protein to appear in aqueous humor and vitreous. It should be used with caution in patients who have history of uveitis.
7- Macular Edema
For the same reason as above and especially in patients who are aphakic and pseudophakic patients with ruptured posterior capsule. Xalatan eye drops can diffuse in these cases to the back surface of the eye, causing disruption of blood-retina barrier. This disruption will cause fluid and cells to diffuse to retina layers, causing macular edema.
8- Allergy to xalatan or one of its components
Signs and symptoms can range from mild to severe and once you have allergic reaction you should stop the medication directly and contact your eye doctor or visit the emergency room as soon as possible. These signs and symptoms are skin rash, red eye, eyelids and lips swelling, eye discharge, difficulty breathing with swelling of tongue and throat.
9- Systemic side effects
Some of the systemic side effects are cough with breathing problems, flu-like symptoms, palpitations, angina pain. Systemic side effects of xalatan eye drops are rare but still dangerous and once you have any of these symptoms you should stop the medication and contact your doctor or the nearest emergency room as soon as possible. Flu-like symptoms such as cough, sneezing, sore throat are the most common systemic symptoms.