Voltaren Ophtha Eye Drops
Publish date 06-03-2016


Voltaren Ophtha Eye Drops

 

 

 

Voltaren Ophtha Eye Drops



Voltaren Ophtha or diclofenac ophthalmic is type of Non Steroidal Anti Inflammatory Eye drops that is used as anti inflammatory and analgesic eye drops to reduce ocular pain and swelling.


Voltaren Ophtha Eye Drops description


Multidose Bottle
Comes on 3 ml and 5 ml, slightly yellow aqueous solution.

Single Use
Each unit contains 0.3ml and preservative free. Each box contains 40 single units.



Ingredients

Active Ingredients
One mL of Voltaren Optha contains 1 mg of diclofenac sodium in both Multidose and single use.

Inactive ingredients

For Multidose bottle
disodium edetate, hydroxypropyl gamma cyclodextrin (CDs), hydrochloric acid, propylene glycol, trometamol, tyloxapol and water for injections.

Single use unites
PEG-35 castor oil, boric acid, trometamol and water for injection.

Preservatives
Benzalkonium chloride 50μg/mL in multidose Bottle. Single use units are preservative free.



Special Precautions for Storage

Multidose Bottle:

1- Do not store above 25°C.

2- Bottle should be closed immediately after use.

3- Do not use for more than one month after opening bottle.

4- All Eye Drops must be kept out of the reach and sight of children.

Single Use Bottle

1- Should be kept in the refrigerator (2-8 degrees C) until it is time to use them.

2- Once the unit is opened, the contents may be kept at room temperature (below 25 degrees C) for up to one month.

3- Discard each single dose unit and any remaining solution in it immediately after use.



Mechanism of action

 

 

 

Diclofenac Ophthalmic inhibits the productions of Prostaglandins which play important roles in inflammation and cause pain, swelling and pain.
Another important action of prostaglandins is pupil miosis.

iosis means that the pupil gets smaller in size and this is a very important factor during cataract surgery because miosed people can make the cataract surgery very difficult. Before cataract surgery, Diclofenac Ophthalmic is give 3 to 5 days before cataract surgery in order to decrease the risk of intra-operative miosis of pupil.

Prostaglandins can cause disruption of blood ocular barrier. This barrier prevents the leakage of fluid from blood vessels. With inflammation and due to prostaglandins, this barrier becomes weak and fluid leakage to the retinal layer can occur, causing macular edema.



Indications of Voltaren Ophtha Eye Drops

1- After Cataract surgery to reduce pain, swelling and inflammation.

2- Post refractive surgery such as post Lasik, PRK and cross linking treatment for keratoconus.

3- To reduce the incidence of intraoperative miosis during cataract surgery.

4- To reduce the incidence of post cataract surgery macular edema.

5- For patients with epi-scleritis.

6- For patients for ocular trauma to reduce pain and photophobia.



Contraindications Of Voltaren Ophtha Eye Drops

1- Known hypersensitivity or allergy to one of its ingredients.

2- Patients with history of Asthma.

3- History of Urticaria, difficulties in breathing and acute rhinitis to aspirin, other prostaglandin-synthetase inhibiting activity or other NSAIDs.



Precautions

1- Don’t use this eye drops when you are wearing contact lenses. Take off your contact lens and wear them again after 10 minutes of eye drops applications.

2- Tell your doctor about systemic disease that you have such as known bleeding tendencies because NSAIDs have the potential for increasing the bleeding time.

3- Tell your doctor if you have any systemic diseases or any medications that you are on because sometimes there is interaction between Voltaren and other medications.



Side Effects of Voltaren Ophtha Eye Drops

 


1- The most common side effect is mild eye irritation.

2- Blurred vision immediately after instillation of the eye drops.

3- Punctate Keratitis.

4- Hypersensitivity reaction such as red eye, itchy eye, eyelid edema, rash, eczema.

5- Systemic allergic reactions such as shortness of breath, rash, face swelling, hypotension and shock. If you notice these symptoms, you should stop using the eye drops and contact emergency room as soon as possible.

 

 

 

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