Corneal Cross Linking

Corneal Cross Linking with Yellow Riboflavin Eye drops © 2019 American Academy of Ophthalmology

Corneal Cross Linking Shown to Improve Visual Acuity and Reduce Higher-Order Aberrations at the 2 Year Mark



For patients who experience conditions such as keratoconus, corneal collagen cross linking has shown to improve their visual acuity and, in turn, improve their quality of life. The results of topographical report outcomes in these patients at 6, 12 and 24 months following the cross linking surgical procedure have shown continual improvement in the corneal aberrations that these patients formerly suffered with and this, in turn, improved the uncorrected visual acuity of these patients.


Studies Show that Corneal collagen Cross Linking Really Does Work

In a study reported in Ocular Surgery News, 2014, corneal cross linking was shown to improve the overall vision and corneal shaping of 42 eyes tested. The interval of time between diagnosis of keratoconus and the cross linking treatment was, on average, 2.2 years.

The participants underwent topographical testing prior to the procedure and at 6 month intervals, up to 24 months following the procedure.



The findings of the topographical results were that the keratometry decreased, as well as the coma, trefoil, secondary astigmatism, secondary coma and secondary trefoil. In other words, the corneas of the test subjects were greatly improved by the cross linking procedure.

The resulting improved visual acuity, uncorrected, was due mainly to the improvements in the patients atypical keratometry, which is simple measurements of the steep and flat axis of the irregular astigmatism experienced by patients with keratoconus.

The improvement in corneal aberrations, due to the collagen cross linking procedure is now thought of as more of a refractive procedure than a treatment of any specific disease, which is debatable. Unlike patients who undergo Lasik as a cosmetic procedure to rid themselves of glasses, patients with keratoconus don’t have the luxury of picking up a pair of glasses and having near perfect vision.

In any event, the important point here is that there are options for patients suffering from keratoconus  that have proven efficacy, according to the results of these studies.




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