Endophthalmitis after Intravitreal Injection



Submitted by moony on Thu, 08/01/2019 - 17:16
South Africa
Did you perform any surgery for the eyes?

Avastin, Lucentis, Ozurdex injections since 2017

Do you suffer from pre-existing illnesses in the eye?

Retinal Vein occlusion

Do you suffer from any diseases in the body?

High blood pressure

Do you use any eye drops?

Vigamox, Pred Forte, Isopto Atropine

Do you wear Contact lenses or Eyeglasses?

Reading glasses





On Thursday the 25th July I had a Luncentis injection. I have been having these injections monthly for the past two years for vein occlusion. On the Sunday evening my I started losing my vision and my eye was bloodshot.

I went to my ophthalmologist immediately and he said I had endophthalmitis and he referred me to another ophthalmologist who I saw first thing on Monday morning.He immediately did a tap and gave me an antibiotic injection into the eye and I was told to insert Vigamox and Pred-Forte every hour and Isopto Atropine twice a day.

The culture came back with a result of "no growth." On Tuesday the ophthalmologist said there was a slight improvement and to carry on with the drops. This morning my sight seemed to be coming back a bit and I can now see my hands and colours.

I went back to the ophthalmologist this morning and he said the infection had gone but suggested I have a vitrectomy today to clean out the pus etc in my eye from the infection. I told him that seeing there is an improvement I would prefer to wait a few more days.

Do you think it is necessary for me to have the vitrectomy?

Will the pus clear on its own by constant use of the eye drops?


Thanks for your Question

That is good that you had some improvement with these eye drops alone without intravitreal injection of antibiotics. No growth in vitreous tap culture doesn't mean you have no infection.

I also prefer to remove any pus in the vitreous with vitrectomy as this pus is releasing toxins and enzymes which can destroy retinal cells and the sooner you remove it the better.